Current Research & Innovations
| Title |
Biventricular Pacing After Cardiopulmonary Bypass |
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| Trial Start Date |
4/1/2007 |
| Trial End Date |
6/21/2012 |
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| Principal Investigator |
Henry Spotnitz, MD |
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| Description |
The purpose of this study is to investigate the efficacy of optimized temporary biventricular pacing in patients undergoing open-heart surgery with preoperative left ventricular dysfunction and an intraventricular conduction delay.
This study will compare extended temporary biventricular pacing versus no pacing by assessing patients randomized to the two groups over three time points using different measures of cardiac output.
Results from this research will demonstrate whether temporary biventricular pacing improves cardiac output after open-heart surgery and whether ventricular pacing site, right-left ventricular delay, and atrioventricular delay optimization increase cardiac output in this setting. Success would lead to the development of recommendations for use of biventricular pacing post-operatively, and would stimulate the development of pacemakers with appropriate features.
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| Inclusion Criteria |
Congestive heart failure
LVEF <41%
IVCD >99 msec (≥120 msec)
Cardiac surgery with CPB OR Mitral & aortic valve replacement |
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| URL |
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| Clinical Areas |
Cardiac |
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| Contact |
For more information, please contact
Vinay Yalamanchi,
Phone: 212-305-5319
E-mail: vy2101@columbia.edu
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