Current Research & Innovations
| Title |
Invasive Monitoring Attenuation through Gene Expression |
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| Trial Start Date |
10/4/2006 |
| Trial End Date |
5/3/2007 |
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| Principal Investigator |
Mario C. Deng, |
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| Description |
The Invasive Monitoring Attenuation through Gene Expression (IMAGE) Multicenter Study (please see attached Columbia-IRB-approved Study Description) is enrolling stable heart transplant recipients 12-60 months after heart transplantation. The hypothesis to be tested is that gene-expression-based (Allomap blood test) monitoring is not inferior to biopsy-based monitoring. The design is 1:1-randomization to either gene-Expression based or biopsy-based monitoring strategy and follow-up for >1 year.
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| Inclusion Criteria |
1. Heart transplant recipients who are in the 2nd to 5th year (>1260
months) posttransplant.
2. Age >=¥18 years.
3. Stable outpatient being seen for routine monitoring of rejection.
4. Left ventricular ejection fraction >=¥45% by Echocardiography, Multiple Gated Acquisition (MUGA) scan, or
ventriculography at study entry (baseline / enrollment study)
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| URL |
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| Clinical Areas |
Cardiac |
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| Contact |
For more information, please contact
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