Collaborative Investigation of Non-syndromic Cleft Heredity (CINCH) This is a multi-center trial (Harvard, Columbia, and Vanderbilt Universities) of potential genetic patterns of nonsyndromic cleft lip and/or palate. We hope to study the genetic patterns (polymorphisms) to define potential combinations of polymorphisms that can predict the occurence of cleft lip and/or palate.
(June Wu, MD)