Purpose

Prior research suggests that omega-3 fatty acids may help people with depression. This research study looks at how omega-3 fatty acids act on the brain, using MRI and PET scans. Participants will have brain scans before and after taking fish oil supplements for 6 weeks. If you are eligible and choose to participate, you will receive FREE fish oil supplements during the first 6 weeks of the study, 6 months of outpatient treatment for Major Depressive Disorder at NO COST to you and $300 compensation for your time and effort.

Type of Study: Observational Type
Setting of Study: outpatient
Clinical Trials.gov number: 
Providing Clinical Treatment?: Yes
No Cost Treatment?: Yes
Care is provided in languages: English

Study Activities

Filling Out Forms
Computer Tasks
Blood Samples
Blood Samples for DNA
PET Scan
MRI Scan
Provides Payment: Compensation for study related procedures

Eligibility

Ages Eligible for Study: 18 Years - 55 Years
Genders Eligible for Study: Both
This study is recruiting Healthy Volunteers.

Criteria

Inclusion Criteria:
Ages 18 to 55
Currently depressed
This study is also recruiting healthy volunteers, who will receive FREE fish oil supplements and $300 compensation.

Location: 
Clinic: Neuroscience Clinic for Mood and Personality Disorders
Division: Neuroscience

Study chairs or principal investigators:
M. Elizabeth Sublette M.D., Ph.D., Principal Investigator

Co-investigators:
J. John Mann,
Ramin Parsey,