Purpose

This study uses brain-imaging technology to visualize and research changes in brain chemistry that may cause an episode of depression in patients with bipolar disorder. You will undergo two PET scans and an MRI scan. In exchange for study participation you will receive up to six months of outpatient treatment or up to two months of inpatient treatment. You will be treated with either lithium or Lamictal, based on your clinical needs.

Type of Study: Clinical Trial
Setting of Study: both
Clinical Trials.gov number: 
Providing Clinical Treatment?: Yes
No Cost Treatment?: Yes

Study Activities

Blood Samples
PET Scan
MRI Scan
Psychophysiology measurements

Eligibility

Ages Eligible for Study: 18 Years - 65 Years
Genders Eligible for Study: Both
This study is not recruiting Healthy Volunteers.

Criteria

Inclusion Criteria:
Ages 18 to 65 years old
Meets criteria for Bipolar Disorder
Currently depressed


Links
The Division of Molecular Imaging and Neuropathology Website

Location: 
Clinic: Neuroscience Clinic for Mood and Personality Disorders
Division: Neuroscience

Study chairs or principal investigators:
Ramin V. Parsey M.D., Ph.D., Principal Investigator

Co-investigators:
Maria Oquendo,