Purpose

This study will develop strategies for early detection and primary prevention of mood disorders and associated impairment in adolescent children of parents with Bipolar Disorder.

Type of Study: Clinical Trial
Setting of Study: outpatient
Clinical Trials.gov number: NCT00338806
Providing Clinical Treatment?: Yes
No Cost Treatment?: Yes

Study Activities

Filling Out Forms
Provides Payment: Compensation for study related procedures

Eligibility

Ages Eligible for Study: 12 Years - 17 Years
Genders Eligible for Study: Both
This study is not recruiting Healthy Volunteers.

Criteria

Inclusion Criteria:
For Parents:
1. Diagnosis of BD I or BD II
2. Currently in partial or full remission from a depressive or manic episode.
3. Speaks English or Spanish
4. Under active clinical care

For Adolescents:
1. Speaks English or Spanish
2. Presence of at least one current DSM-IV criterion A mood symptom plus at least one criterion B depression or mania symptom
3. Depression, irritability, anhedonia, or elated mood scores on KSADS-PL
4. Mania symptom scored at level 2 or 3 on the KSADS-PL
5. Score of less than 40 on CDRS-R scale
6. Score of less than 15 on the YMRS scale
7. Mild to moderate functional impairment, defined as a score of more than 61 but less than 75 on the CGAS

Location: 1051 Riverside Drive Unit 24 Room 2703 New York, NY 10032
Clinic: 
Division: Division of Epidemiology

Study chairs or principal investigators:
Helen Verdeli Ph.D., Principal Investigator

Co-investigators:
,