Purpose

This twelve-week study uses the medication duloxetine (Cymbalta) for the treatment of mild-to-moderate chronic depression in older adults (age 60+). After the twelve-week medication trial, additional treatment will be available for a minimum of three months.

Type of Study: Clinical Trial
Setting of Study: outpatient
Clinical Trials.gov number: 
Providing Clinical Treatment?: Yes
No Cost Treatment?: Yes

Study Activities

Filling Out Forms
Provides Payment: Reimbursement for transportation
Provides Payment: Compensation for study related procedures

Eligibility

Ages Eligible for Study: 60 Years - 95 Years
Genders Eligible for Study: Both
This study is not recruiting Healthy Volunteers.

Criteria

Inclusion Criteria:
1) Diagnosis of dysthymic disorder; 2) Age 60-95; 3) Mini-Mental State Score > 23; 24-item Hamilton Depression Rating Scale score 12-25; 5) Assessed as having capacity and willing to provide informed consent

Location: New York State Psychiatric Institute Unit 126 1051 Riverside Dr. New York, NY
Clinic: Mid and Late Life Depression
Division: Biological Psychiatry

Study chairs or principal investigators:
D.P. Devanand M.D., Principal Investigator

Co-investigators:
Harold Sackeim,
Mitchell Nobler,