Dopamine Release in Major Depression Please refer to this study by identifier 4949
Principal Investigator(s) Franklin Schneier
Purpose
The purpose of this study is to study a brain chemical called dopamine in persons with and without depression. This study will use a technique called Positron Emission Tomography (PET), the radioactive “tagged” investigational drug [11C]raclopride, and a single dose of the drug amphetamine. PET is a technique for taking "pictures" of chemical activity in the brain by detecting the radioactive signal of a "tagged" drug. To help determine the location of the signal in the brain, an MRI scan will also be done. 24 subjects will participate in this study.
Type of Study: Observational Type Setting of Study: outpatient Clinical Trials.gov number: Providing Clinical Treatment?: Yes No Cost Treatment?: Yes
Study Activities
Filling Out Forms Blood Samples PET Scan MRI Scan Provides Payment: Compensation for study related procedures
Eligibility
Ages Eligible for Study: 18 Years - 55 Years Genders Eligible for Study: Both
This study is not recruiting Healthy Volunteers.