Research Faculty

Address
630 West 168th Street,
PH 15W 1562
New York, NY 10032


Phone: 212-305-7676
Fax: 212-305-5958

ajk55@cumc.columbia.edu
Education and Training
D.D.S., Columbia University
College of Dental Medicine 2003

Oral & Maxillofacial Pathology
Residency, Columbia University
Medical Center 2006

Fellowship, American Academy
of Oral and Maxillofacial
Pathology 2006

Diplomate, American Board
of Oral and Maxillofacial
Pathology 2006

Affiliations
Head and Neck

Training Activities
Program Director
Oral & Maxillofacial Pathology
Residency at CUMC
Angela J. Yoon, DDS, MPH, MAMSc
John W. Richter Associate Professor of Oral Pathology
College of Dental Medicine & Dept. of Pathology and Cell Biology at CUMC
Research Summary

- Translational studies to develop novel molecular risk assessment strategies, and to improve therapies for oral squamous cell carcinoma.

- Clinical trials, both investigator-initiated and multi-centered, to evaluate the efficacy of chemopreventive agents of oral cancer.
Selected Publications

*Yoon AJ, Shen J, Santella RM, Zegarelli DJ, Chen R, Weinstein IB. Activated checkpoint kinase 2 expression and risk for oral squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2007;1:2768-2772 (NIHMSID # 70903).

*Yoon AJ, Shen J, Wu H, Angelopoulos D, Singer S, Chen R, Santella RM. Expression of Checkpoint Kinase 2 and Histone 2AX in Exfoliative Oral Cells Following Exposure to Ionizing Radiation. Radiat. Res. 2009;171:771-775 (NIHMSID # 439211).

Zavras AI, Yoon AJ, Chen MK, Lin CW, Yang SF. Metallothionein-1 genotypes in the risk of oral squamous cell carcinoma. Ann Surg Oncol. 2011;18:1473-1483.

Yoon AJ, Kuo WH, Lin CW, Yang SF. Role of ERCC5 polymorphism in risk of hepatocellular carcinoma. Oncol Letters. 2011;2:911-914.

Yoon AJ, Zavras AI, Chen MK, Lin CW, Yang SF. Association between Gly1619ARG polymorphism of IGF2R domain 11 (RS629849) and advanced stage of oral cancer. Med Oncol 2012;29:682-685.

Yoon AJ, Cheng B, Philipone E, Turner R, Lamster IB. Inflammatory biomarkers in saliva: assessing the contribution of diabetes mellitus and periodontal status to the oral inflammatory burden. J Clin Periodontol 2012;39:434-440.

*Yoon AJ, Shen J, Santella RM, Philipone EM, Wu HC, Eisig SB, Blitzer A, Close LG, Zegarelli DJ. Topical application of green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) for prevention of recurrent oral neoplastic lesions. JOFS 2012;4:43-50 (NIHMSID # 439216).

Zavras AI, Yoon AJ, Chen MK, Lin CW, Yang SF. Association between polymorphisms of DNA repair gene ERCC5 and oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2012;114:624-629.

*Yoon AJ, Wang S, Shen J, Robine N, Philipone E, Oster M, Nam A, Santella RM. Prognostic value of miR-375 and miR-214-3p in early stage oral squamous cell carcinoma. Am J Transl Res 2014;6:580-592.

Current Projects

Assessing the prognostic utility of microRNA-based markers for oral cancer patients. This study aims to create a point-of-care clinical application of individualized microRNA profiles in oral cancer prognostication and treatment selection guidance.

Honors and Awards

7/2015 - Interdisciplinary appointment in the Department of Pathology and Cell Biology at the Columbia University Medical Center

5/2013 - The Edward V Zegarelli Teaching Award, CU CDM
Committees , Council, and Professional Society Memberships

• American Association for Cancer Research
• American Academy of Oral and Maxillofacial Pathology
• The American Academy of Oral Medicine
• United States and Canadian Academy of Pathology
• American Dental Association
• Omicron Kappa Upsilon Fraternity
Keywords

Oral lesions, epithelial dysplasia, oral squamous cell carcinoma, prognostic biomarkers, microRNA

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