Research Faculty

Address
622 West 168 Street
PH 10-105
New York, NY 10032

Phone: 212-305-3213
Fax:

Sc2752@cumc.columbia.edu
Education and Training
Groningen University, Leiden University Medical Center

Collaborations
OBGYN (Carolyn Westhoff, Ronald Wapner, Joy Vink, Kristin Meyers), ENDO (John Bilezikian, Elizabeth Shane, Shonni Silverberg), HEME-ONC (Gary Schwartz, Suzanne Lentzsch, Matt Maurer, Cathy Crew, Dawn Hershman), ID (Michael Yin, Christine Kubin), NEPHR (Sumit Mohan), EXP THER (Owen O’Connor, Don Landry, Shixian Deng), Thoracic Surgery (d’Ovidio), Pediatric HEME (Gary Brittenham, Margareth Lee), Pediatric ONC (Andrew Kung, Monica Bhatia)

Affiliations
Res
Medicine
Serge Cremers, PhD, PharmD
Associate Professor in Pathology and Cell Biology and Medicine
Director, Clinical Pharmacology and Toxicology Laboratory
Director, Biomarkers Core Laboratory
Research Summary

I am interested in clinical and translational pharmacokinetics of drugs as well as in biochemistry of metabolic bone diseases.
Service Activities

Clinical Pharmacology, Therapeutic Drug Monitoring and Endocrinology
Selected Publications

Thomas T, Petrie K, Shim J, Abildskov KM, Westhoff CL, Cremers S. A UPLC-MS/MS method for therapeutic drug monitoring of etonogestrel. Ther Drug Monit 2013; 35(6):844-8.

Cusano NE, Maalouf NM, Wang PY, Zhang C, Cremers SC, Haney EM, Bauer DC, Orwoll ES, Bilezikian JP. Normocalcemic hyperparathyroidism and hypoparathyroidism in two community-based non-referral populations. J Clin Endocrinol Metab 2013;98(7):2734-41.

Yoshida K, Reeves C, Vink J, Kitajewski J, Wapner R, Jiang H, Cremers S, Myers K. Cervical Collagen Network Remodeling in Normal Pregnancy and Disrupted Parturition in Antxr2 Deficient Mice. J Biomech Eng. 2014, 136(2):021017.

Cohen A, Stein EM, Recker RR, Lappe JM, Dempster DW, Zhou H, Cremers S, McMahon DJ, Nickolas TL, Müller R, Zwahlen A, Young P, Stubby J, Shane E. Teriparatide for Idiopathic Osteoporosis in Premenopausal Women: A Pilot Study. J Clin Endocrinol Metab 2013; 98(5):1971-81.

Westhoff CL, Torgal AH, Mayeda ER, Petrie K, Thomas T, Dragoman MV, Cremers S. Pharmacokinetics and ovarian suppression during use of a contraceptive vaginal ring in normal weight and obese women. J Obstet Gynecol 2012; 207(1):39.e1-6.

Thomas TA, Broun EC, Abildskov KM, Kubin CJ, Horan J, Yin MT, Cremers S. High Performance Liquid Chromatography-Mass Spectrometry (LC-MS) assay for polymyxin B1 and B2 in human plasma. Ther Drug Monit 2012; 34(4):398-405.

Nickolas T, Cremers S, Zhang A, Stein EM, Cohen A, Chauncey R, Nikkel L, Liu X, Boutroy S, Yin M, Staron M, Leonard M, McMahon D, Dworakowski E, Shane E. Discriminants of prevalent fractures in chronic kidney disease. J Am Soc Nephrol 2011, 22(8):1560-72.

Papapoulos SE, Cremers SCLM. Bisphosphonate is released in the circulation for at least 8 years after cessation of long-term treatment of children with osteoporosis. N Engl J Med 2007;356:1075-1076.

Committees , Council, and Professional Society Memberships

AACC, IATDMCT, ASBMR, KNMP, NVZA, NVKF-B
Keywords

Pharmacokinetics, Therapeutic Drug Monitoring, TDM, clinical pharmacology, bone, biochemistry, bone turnover markers
top
 
 
Contact the Pathology Webmaster at PathWebMaster@columbia.edu