Research Faculty

Address
Ph 7E-122D
622 W. 168th Street,
New York, NY 10032

Phone: 212-305-8334
Fax: 212-305-7134

lm23@columbia.edu
Letty Moss-Salentijn, DDS, PhD
Dr. Edwin S. Robinson Professor of Dentistry (in Anatomy and Cell Biology);
Vice Dean for Academic Affairs in the College of Dental Medicine
Research Summary

My research has focused primarily on aspects of the Functional Matrix theory, which was developed originally in Dr. Melvin Moss- laboratory. After I joined the faculty, Dr. Moss and I worked in a shared laboratory and worked on the effects of the functional matrix on fetal and postnatal cranial growth. In addition to our shared projects (e.g. logarithmic growth patterns of the skull; finite element analysis of skull growth) my efforts were concentrated on the growth of cartilages: growth plates in long bones and synchondroses in the skull. Experimental methods included denervation experiments , 3-D analysis of chondrocytic columns in growth plates, computer-based analysis of random growth patterns of the clones that gave rise to the columns, and a combination of kinematics and chondrocytic clone patterns.

A secondary focus of my research was the description of particular characteristics of dental tissues and comparative odontogenesis.

In recent years I have been involved in the development of new media applications to enrich the teaching of courses in oral histology and embryology, clinical anatomy, molecular mechanisms, as well as several graduate courses.

Service Activities

Provost's Task Force, Teaching Resource Center
Columbia University Academic and Strategic Planning Subcommittee
Site Visitor - ACHE Middle States Association
Provost's Intellectual Property Policy Committee
Columbia University Senate (Education Committee - co-chair; Faculty Affairs Committee - co-chair; Executive Committee)

Selected Publications

Melvin L. Moss and Letty Salentijn : The unitary logarithmic curve descriptive of human mandibular growth. Acta Anat., 78:532-542, 1971

Letty Moss-Salentijn : Studies on dentin.3. Vestigial lacteal incisor teeth of the rat. Acta Anat., 92:329-351, 1975
Letty Moss-Salentijn: Experimental retardation of early endochondral ossification in the phalangeal epiphyses of rat. Proc.Finn.Dent.Soc., 77:129-138, 1981

M. Shinozuka, A. Tsurui, T. Naganuma, M. L. Moss and L. Moss-Salentijn: A stochastic-mechanical model of longitudinal long bone growth. J.Theor.Biol.,108: 413-436, 1984

M. L. Moss, R. Skalak, H. Patel, K. Sen, L. Moss-Salentijn, M. Shinozueka, and H. Vilmann : Finite element method modeling of cranio-facial growth. Am. J. Orthodontics, 87:453-472, 1985

Letty Moss-Salentijn: Reattachment of muscles to developing cranial elements. Nova Acta Leopoldina NF 58 (262): 257-265, 1986

Letty Moss-Salentijn, Melvin L. Moss, Masanobu Shinozuka, and Richard Skalak : Morphological analysis and computer-aided, three-dimensional reconstruction of chondrocytic columns in rabbit growth plates. J.Anat.,151: 157-167,1987

Letty Moss-Salentijn, N. F. Kember, M. Shinozuka, W. F. Wu and Anjana Bose: Computer simulations of chondrocytic clone behavior in rabbit growth plates. J. Anat., 175:7-17, 1991

Stephen C. Cowin, Letty Moss-Salentijn and Melvin L. Moss: Candidates for the mechanosensory system in bone. J. Biomech. Eng. 113: 191-197, 1991

M. L. Moss, L. Moss-Salentijn, G. Hasselgren, H. Ling: A quantum biological hypothesis of human secondary dentinogenesis. Medical Hypotheses 64: 479-486, 2005

Textbooks

Letty Moss-Salentijn, Edmund Applebaum and Alfred Lamme: Orofacial Histology and Embryology. A Visual Integration TEXTBOOK/ATLAS, F. A. Davis Company, Philadelphia, 1972

Letty Moss-Salentijn and Marlene Hendricks-Klyvert: Dental and Oral Tissues. An Introduction. (Editions 1-3) Lea & Febiger, Philadelphia, 1980, 1985, 1990. Translated in Italian and Japanese.


Honors and Awards

Presidential Award for Excellence in Teaching (Columbia University)
Committees , Council, and Professional Society Memberships

American Association of Anatomists
American Association of Clinical Anatomists
American Association of Physical Anthropologists
American Society of Biomechanics
American Dental Education Association
Fellow, Royal Microscopical Society
International Association of Dental Research


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