Research Faculty

Address
161 Fort Washington Ave,
Irving Pavilion 862
New York, NY 10032


Phone: 212-305-0527
Fax: 212-305-0771

dld6@columbia.edu
Education and Training
1975 A.B. Harvard College Cambridge
1979 M.D. Cornell University Medical College New York

David Diuguid, M.D.
Associate Professor of Clinical Pathology; Associate Professor of Clinical Medicine
Selected Publications

1. Esmon, C.T., Owen, W.G., Diuguid, D.L., and Jackson, C.M. The action of thrombin on blood clotting factor V: conversion of factor V to a prothrombin binding protein. Biochimica et Biophysica Acta 310:289 294 (1973)

2. Diuguid, D.L., Rabiet, M.J., Furie, B.C., Liebman, H.A., and Furie, B. Molecular basis of Hemophilia B: A defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor. Proc. Natl. Acad. Sci., U.S.A. 83: 5803 5807 (1986)

3. Diuguid, D.L., Rabiet, M.J., B.C. Furie, and B. Furie. Molecular defects of Factor IX Chicago 2 (Arg 145 His) and Prothrombin Madrid (Arg 271 Cys): Arginine mutations that preclude zymogen activation. Blood 74: 193-200 (1989)

4. Ware, J., Diuguid, D.L., Liebman, H.A., Rabiet, M.J., Kasper, C.K., Furie, B.C., Furie, B., and Stafford, D.W. Factor IX San Dimas: Substitution of glutamine for arginine -4 in the propeptide leads to incomplete -carboxylation and altered phospholipid binding properties. J. Biol. Chem. 264: 11401-11406 (1989)

5. Furie, B., Diuguid, C.F., Jacobs, M., Diuguid, D.L., and Furie, B.C. Randomized prospective trial comparing the native prothrombin antigen and the prothrombin time for monitoring oral anticoagulant therapy. Blood 75: 344-349 (1990)
Honors and Awards

1970
Rensselear Medal

1971
Bausch and Lomb Science Award

1971 - 1975
National Achievement Scholarship Award

1977 Mosby Book Award


top
 
 
Contact the Pathology Webmaster at PathWebMaster@columbia.edu